The HPA Axis

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The stress response is primarily governed by the hypothalamic-pituitary-adrenal (HPA) axis. Incoming sensory messages are screened by the limbic system in the mid-brain – this includes the hippocampus, amygdala and prefrontal cortex, as well as the hypothalamus. If these messages are recognised as stressful, the hypothalamus signals the pituitary to stimulate the adrenals to release...

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